Johnson and Johnson Talvey antibody-based medicine Talvey received FDA approval rapidly. This advances multiple myeloma and blood cancer treatment.
Only Talvey targets myeloma cells’ GPRC5D protein. The Sylvester Comprehensive Cancer Center’s Myeloma Program director, Dr. Ola Landgren, thinks this is a major advance.
Talvey accomplishes things uniquely. The FDA’s fast clearance process expedites life-saving drugs that fill clinical gaps. Dr. Landgren thinks we need new medications to fix myeloma treatment.
Talvey (talquetamab) is given to multiple myeloma patients with a dismal outlook who have had at least four therapies. Doctors administer the shot monthly or bimonthly.
Myeloma patients who have tried everything and are still sick do well in clinical trials. Dr. Landgren estimates that 70% of patients who have not responded to any of the four treatments will respond to Talvey.
But the fact that myeloma tumor cells can become resistant to treatment emphasizes how crucial it is to research and develop new therapies constantly. Talc may lower immunity, making individuals unwell. Dr. Landgren says side effects include taste alterations, dry mouth, and difficulty eating.
Careful doctors can monitor a patient’s immune system and ensure safety. Fever and immune system reactions are treated with Talvey’s drug’s first doses in hospitals. How to start giving outpatients medications is being researched.
New therapies like Talvey give myeloma patients hope. Dr. Landgren believes that a high rate of minimal residual disease negativity (MRD-negative) improves treatment when immunotherapies are employed instead of chemotherapy.
Myeloma survivors are growing. They used to last one to two years, but now they can last 10–20 years or longer. Dr. Landgren’s dedication to curative therapy and other professionals shows how difficult it is to improve patient outcomes.
35,000 Americans get myeloma, a rare cancer. Specialized treatment is needed. Dr. Landgren thinks myeloma doctors can improve prognoses and quality of life by changing their treatment.
Myeloma patients have hope as the FDA approved Talvey quickl