Revolutionizing Parkinson Diagnosis : Neurology published a Parkinson’s study today. The problem was found through retinal scans and AI. Researchers found new information by carefully studying the AlzEye collection and comparing it to the UK Biobank database.
These vast data sets show that Parkinson’s disease, which affects 0.1–0.2% of the world’s population, has modest but significant symptoms. The AlzEye collection used the INSIGHT database of retinal images and clinical data.
“Oculomics” is a new area that uses eye scans to study nervous system diseases. Eye scans show schizophrenia, MS, and Alzheimer’s, interesting. Eye scans increase hypertension, heart disease, and diabetes risk.
Doctors have examined all patient health issues with the eye since the beginning. High-resolution retinal images are now taken utilizing “optical coherence tomography” in ophthalmology. These photos show a retina cross-section with one-thousandth of a millimeter resolution and the skin’s cellular matrix without damage.
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Researchers can sort millions of OCTs in nanoseconds utilizing advanced computers. This requires a lot of time. The high-tech computer uses “machine learning,” an artificial intelligence, to reveal secret body information in these photos. Oculomics’ potential is shown.
Siegfried Wagner, a distinguished UCL Institute of Ophthalmology and Moorfields Eye Hospital eye expert led the investigation. “He said, “Eye scans taught us amazing things. They are almost ready to find sick people and help them change their lives before being sick.
The study indicated everyone worked well together. Moorfields Eye Hospital, University College Hospital London, and other NIHR Biomedical Research Centres helped. Long-term NHS partnerships increased this project’s quality and scope.
University Hospitals Birmingham Professor Alastair Denniston says, “When eye data is combined with cutting-edge technology, it gives us insights previously invisible to the human eye.” This may drastically change early-stage Parkinson’s diagnosis.
Miss Louisa Wickham, Moorfields owner, thinks imaging might change public health planning. OCT scans beat brain imaging in speed, cost, and usability.
Parkinson’s disease is caused by dopamine deficiency and ocular INL alterations after death. OCT scans have shown structural abnormalities in Parkinson’s disease, although these investigations are unclear. This study demonstrated decreasing INL and GCIPL in ganglion cells. Even after controlling for other conditions, smaller layers are connected to Parkinson’s.
More research is needed to discover if Parkinson’s brain changes reduce GCIPL or INL. If easier to interpret, eye scans could identify, predict, and cure Parkinson’s. This study lacks Parkinson’s disease clinical evidence to link retinal abnormalities to the disease.
